slc24a5 Antibody

Code CSB-PA673244XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) slc24a5 Polyclonal antibody
Uniprot No.
Target Names
slc24a5
Alternative Names
slc24a5 antibody; nckx5 antibody; Sodium/potassium/calcium exchanger 5 antibody; Na(+)/K(+)/Ca(2+)-exchange protein 5 antibody; Protein golden antibody; Solute carrier family 24 member 5 antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) slc24a5 protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Cation exchanger which plays a central role in pigmentation, possibly by participating in ion transport in melanosomes. Probably transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Gene References into Functions
  1. golden mutants are associated with diminished number, size and density of melanosomes; golden encodes a putative cation exchanger slc24a5 that localizes to an intracellular membrane, likely the melanosome or its precursor PMID: 16357253
Subcellular Location
Endomembrane system; Multi-pass membrane protein. Note=Localizes to intracellular membranes, likely the melanosomes or their precursors.
Protein Families
Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily
Tissue Specificity
Highly expressed in melanin-producing cells. Colocalizes with melanin biosynthesis marker dct.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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