ncx-9 Antibody

Code CSB-PA152727XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ncx-9 Polyclonal antibody
Uniprot No.
Target Names
ncx-9
Alternative Names
ncx-9 antibody; C13D9.8 antibody; Mitochondrial sodium/calcium exchanger protein antibody; Sodium/calcium exchanger 9 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ncx-9 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis (Probable). Required for patterning of neural circuits: functions in the same pathway as RAC-dependent effectors of the unc-6/netrin signaling pathway to set left/ right patterning of the VD/DD GABAergic circuit.
Gene References into Functions
  1. our work reveals the specificity by which the handling by NCLX of calcium exchange can map to neural circuit patterning and axon guidance decisions during development PMID: 28196860
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily
Tissue Specificity
Expressed in the seam cells of the organism. Expression is visible in the seam cells across all larval stages, and expression persists into the adult stage of the organism.
Database Links

KEGG: cel:CELE_C13D9.8

STRING: 6239.C13D9.8

UniGene: Cel.4796

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