gas-1 Antibody

Code CSB-PA856633XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans gas-1 Polyclonal antibody
Uniprot No.
Target Names
gas-1
Alternative Names
gas-1 antibody; K09A9.5 antibody; Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 antibody; mitochondrial antibody; EC 1.6.99.3 antibody; EC 7.1.1.2 antibody; Complex I-49kD antibody; CI-49kD antibody; NADH-ubiquinone oxidoreductase 49 kDa subunit antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans gas-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Gene References into Functions
  1. high levels of complex II negatively regulate longevity in gas-1(fc21) mutant by decreasing the stability of complex I. PMID: 23555681
  2. mutation in a subunit of complex I of the mitochondrial electron transport chain (gas-1) causes Caenorhabditis elegans to be hypersensitive to volatile anesthetics and oxygen as well as shortening lifespan PMID: 15178135
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
Complex I 49 kDa subunit family
Database Links

KEGG: cel:CELE_K09A9.5

STRING: 6239.K09A9.5

UniGene: Cel.8011

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