nep-2 Antibody

Code CSB-PA911065XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans nep-2 Polyclonal antibody
Uniprot No.
Target Names
nep-2
Alternative Names
nep-2 antibody; T05A8.4 antibody; Neprilysin-2 antibody; EC 3.4.24.- antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans nep-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for olfactory plasticity, which is the change from positive chemotaxis to dispersal after prolonged exposure to an odorant. Thought to antagonise snet-1 by degrading excess snet-1 peptides and thus enabling olfactory plasticity.
Gene References into Functions
  1. findings show a peptide, suppressor of NEP-2 (SNET-1), negatively regulates olfactory plasticity; its expression is down-regulated by the pheromone; NEP-2, a homolog of neprilysin, antagonizes SNET-1; this function is essential for olfactory plasticity PMID: 20929849
Subcellular Location
Membrane; Single-pass type II membrane protein.
Protein Families
Peptidase M13 family
Tissue Specificity
Expressed in muscle cells, GLR cells, SMB motor neurons and AIM interneurons.
Database Links

KEGG: cel:CELE_T05A8.4

UniGene: Cel.20256

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