nipblb Antibody

Code CSB-PA551938XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) nipblb Polyclonal antibody
Uniprot No.
Target Names
nipblb
Alternative Names
nipblb antibody; Nipped-B-like protein B antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) nipblb protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May play a structural role in chromatin. Involved in sister chromatid cohesion, possibly by facilitating the cohesin complex loading. Transcription factor, which may promote cortical neuron migration during brain development by regulating the transcription of crucial genes in this process.
Gene References into Functions
  1. Nipbl and mediator cooperatively regulate gene expression to control limb development. PMID: 25255084
  2. The present study focuses on the role of the zebrafish nipblb paralog during neural development. PMID: 24136230
  3. Nipbl-deficient embryos showed changes in the expression of genes involved in the specification of endoderm, which gives rise to gut and provides a substrate for cardiac precursor migration, as well as genes that regulate left-right asymmetry. PMID: 22039349
  4. Nipbl-deficient embryos showed changes in the expression of genes involved in the specification of endoderm, which gives rise to gut and provides a substrate for cardiac precursor migration, as well as genes that regulate left-right asymmetry PMID: 22039349
Subcellular Location
Nucleus.
Protein Families
SCC2/Nipped-B family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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