Nitrophorin-7 Antibody

Code CSB-PA761365XA01RLB
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Product Details

Uniprot No.
Alternative Names
Nitrophorin-7 antibody; NP7 antibody; EC 1.7.6.1 antibody; Nitrite dismutase antibody
Raised in
Rabbit
Species Reactivity
Rhodnius prolixus (Triatomid bug)
Immunogen
Recombinant Rhodnius prolixus (Triatomid bug) Nitrophorin-7 protein
Immunogen Species
Rhodnius prolixus (Triatomid bug)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Converts nitrite as the sole substrate to form nitric oxide gas (NO). NO(2-) serves both as an electron donor and as an electron acceptor. Binds to negatively charged cell surfaces of activated platelets; binds to L-a-phosphatidyl-L-serine (PS)-bearing phospholipid membranes. Once bound on an activated platelet, NP7 releases its stored nitric oxide gas (NO) into the victim's tissues while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also acts as an anticoagulant by blocking coagulation-factor binding sites. Has antihistamine activity; binds histamine with high affinity.
Subcellular Location
Secreted.
Protein Families
Calycin superfamily, Nitrophorin family
Tissue Specificity
Expressed in the endothelial cells of the salivary glands.
Database Links

KEGG: ag:AAS94228

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