ncr-2 Antibody

Code CSB-PA339449XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ncr-2 Polyclonal antibody
Uniprot No.
Target Names
ncr-2
Alternative Names
ncr-2 antibody; npc-2 antibody; F09G8.4 antibody; NPC intracellular cholesterol transporter 1 homolog 2 antibody; Niemann-Pick C1 protein homolog 2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ncr-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in the uptake or utilization of cholesterol. Ncr-1 and ncr-2 act redundantly to prevent dauer larva formation under favorable growth conditions, and are required for the normal functioning of ADF, ASI and ASG neurons.
Gene References into Functions
  1. Mutations in NPC1 in two Brazilian patients with Niemann-Pick disease type C and progressive supranuclear palsy-like presentation. PMID: 17044092
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Patched family
Database Links

KEGG: cel:CELE_F09G8.4

STRING: 6239.F09G8.4

UniGene: Cel.5139

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