Npc2a Antibody

Code CSB-PA893313XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Npc2a Polyclonal antibody
Uniprot No.
Target Names
Npc2a
Alternative Names
Npc2a antibody; NPC2 antibody; CG7291 antibody; NPC intracellular cholesterol transporter 2 homolog a antibody; Niemann Pick type C2 protein homolog antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Npc2a protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Functions redundantly with Npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate.
Gene References into Functions
  1. may play a role in the immune deficiency pathway PMID: 22580186
  2. Data suggest that npc2a functions redundantly with npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate. PMID: 17804599
Subcellular Location
Secreted.
Protein Families
NPC2 family
Tissue Specificity
Broadly expressed with a higher level of expression in many tissues, including midgut, salivary gland and ventral nerve cord.
Database Links

KEGG: dme:Dmel_CG7291

STRING: 7227.FBpp0077492

UniGene: Dm.7263

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