NT5C Antibody

Code CSB-PA837431XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NT5C Polyclonal antibody
Uniprot No.
Target Names
NT5C
Alternative Names
3''-pyrimidine nucleotidase antibody; 5' nucleotidase, deoxy (pyrimidine) antibody; 5' nucleotidase, deoxy (pyrimidine), cytosolic type C antibody; 5''(3'')-deoxyribonucleotidase antibody; 5'(3')-deoxyribonucleotidase, cytosolic type antibody; 5', 3'-nucleotidase, cytosolic antibody; 5-prime,3-prime-nucleotidase, cytosolic antibody; cdN antibody; Cytosolic 5'' antibody; cytosolic 5',3'-pyrimidine nucleotidase antibody; cytosolic type antibody; cytosolic type C,5',3'-nucleotidase antibody; cytosolic,uridine 5'-monophosphate phosphohydrolase 2 antibody; Deoxy 5' nucleotidase 1 antibody; Deoxy-5''-nucleotidase 1 antibody; Deoxyribonucleotidase, cytosolic, 1 antibody; DNT antibody; dNT-1 antibody; dNT1 antibody; Nt5c antibody; NT5C_HUMAN antibody; P5N2 antibody; PN-I antibody; PN-II antibody; Pyrimidine 5-prime nucleotidase 2 antibody; UMPH2 antibody; uridine 5'-monophosphate phosphohydrolase 2 antibody; uridine 5-prime monophosphate hydrolase 2 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) NT5C protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
Gene References into Functions
  1. Data show that PN-I shows a higher affinity for oxynucleosides rather than deoxynucleosides, while the opposite is true for PN-II. PMID: 12418222
  2. Mutation analysis in the P5N-I gene led to the identification of 3 novel mutations PMID: 12714505
Subcellular Location
Cytoplasm.
Protein Families
5'(3')-deoxyribonucleotidase family
Tissue Specificity
Detected in skeletal muscle, heart and pancreas.
Database Links

HGNC: 17144

OMIM: 191720

KEGG: hsa:30833

STRING: 9606.ENSP00000245552

UniGene: Hs.67201

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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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