Nup107 Antibody

Datasheet

Code	CSB-PA254982XA01DLU
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) Nup107 Polyclonal antibody

Uniprot No.

Q9V466

Target Names

Nup107

Alternative Names

Nup107 antibody; CG6743 antibody; Nuclear pore complex protein Nup107 antibody; Nucleoporin Nup107 antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Nup107 protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plays a role in nuclear pore complex (NPC) assembly and maintenance. Required for nuclear import of Mad. Mediates the association between the nuclear pore complex and a subset of active chromatin regions adjacent to lamin-associated domains. Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process. Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope. Regulates female gonad development and oogenesis.

Gene References into Functions

Nup107 knockdown in somatic gonadal cells resulted in female sterility. Transgenic rescue of Drosophila females bearing the Nup107D364N mutation resulted in almost complete sterility, reduced progeny, aberrant eggshells, and disintegrating egg chambers. PMID: 26485283

Subcellular Location

Nucleus, nuclear pore complex. Nucleus envelope. Nucleus membrane. Cytoplasm, cytoskeleton, spindle. Chromosome. Nucleus matrix.

Protein Families

Nucleoporin Nup84/Nup107 family

Tissue Specificity

Expressed in spermatocytes (at protein level).

Database Links

KEGG: dme:Dmel_CG6743

STRING: 7227.FBpp0079710

UniGene: Dm.395

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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