NUBP1 Antibody

Code CSB-PA016142XA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NUBP1 Polyclonal antibody
Uniprot No.
Target Names
NUBP1
Alternative Names
MGC130052 antibody; Cytosolic Fe S cluster assembly factor NUBP1 antibody; Cytosolic Fe-S cluster assembly factor NUBP1 antibody; MGC117406 antibody; MGC130053 antibody; NBP 1 antibody; NBP antibody; NBP1 antibody; NBP35 antibody; nubp1 antibody; NUBP1_HUMAN antibody; Nucleotide binding protein (e.coli MinD like) antibody; Nucleotide binding protein 1 (E.coli MinD like) antibody; Nucleotide binding protein 1 (MinD homolog, E. coli) antibody; Nucleotide binding protein 1 antibody; Nucleotide-binding protein 1 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens (Human)
Immunogen
Recombinant Homo sapiens (Human) NUBP1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure.
Gene References into Functions
  1. The cytosolic soluble P-loop NTPase termed huNbp35 (also known as Nubp1) was identified as an Fe/S protein, and its role in the maturation of Fe/S proteins in HeLa cells, is defined. PMID: 18573874
Subcellular Location
Cytoplasm. Nucleus. Cell projection. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Families
Mrp/NBP35 ATP-binding proteins family, NUBP1/NBP35 subfamily
Database Links

HGNC: 8041

OMIM: 600280

KEGG: hsa:4682

STRING: 9606.ENSP00000283027

UniGene: Hs.81469

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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