NUDT7 Antibody

1. The active and inactive AtNUDX6 proteins induced the expression of thioredoxin-h5 while the active and inactive AtNUDX7 proteins suppressed the accumulation of SA and subsequent gene expression, indicating that AtNUDX6 and 7 proteins themselves play distinct roles in stress responses. [AtNUDX7] PMID: 27095738
2. provide evidence that AtERF1 is important for regulating AtNudt7 during oxidative signaling. PMID: 25451743
3. AtNUDT7 is important for NAD:NADH homeostasis in seeds. PMID: 24504697
4. NUDT7 forms complexes in vitro and in vivo with regulatory proteins involved in signal transduction. PMID: 22068106
5. AtNUDT7 protein levels are induced in response to biotic and abiotic stresses. AtNUDT7 plays an important role in maintaining redox homeostasis, particularly for maintaining NADH:NAD+ balance for normal growth and development. PMID: 20704736
6. Under oxidative stress, AtNUDX7 serves to maintain NAD(+) levels by supplying ATP via nucleotide recycling from free ADP-Rib molecules and thus regulates the defense mechanisms against oxidative DNA damage via modulation of the PAR reaction. [AtNUDX7] PMID: 19656905
7. GFG1 is a key gene linking cellular metabolism and oxidative signaling. PMID: 16328543
8. FMO1 and NUDT7 are important for signaling through an EDS1-dependent but SA-independent branch of plant defense and NUDT7 exerts negative control of EDS1 signaling. [NUDT7] PMID: 16531493
9. functions to modulate the defense response to prevent excessive stimulation, ADP-ribose and NADH are preferred substrates PMID: 17660350
10. structure-activity studies: mutation of specific residues in AtNUDT7 alters function; mutation of residues F73 & V168 disallows dimer formation & enzymatic activity; mutation of residues V69, F73, & V168 disrupts binding to regulatory 14-3-3 protein PMID: 19448856

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KEGG: ath:AT4G12720

UniGene: At.23449