npp-10 Antibody

Code CSB-PA921708XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans npp-10 Polyclonal antibody
Uniprot No.
Target Names
npp-10
Alternative Names
npp-10 antibody; ZK328.5 antibody; Nuclear pore complex protein Nup98-Nup96 antibody; EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 antibody; 98 kDa nucleoporin antibody; Nucleoporin Nup98 antibody; CeNup98); Nuclear pore complex protein Nup96 antibody; 96 kDa nucleoporin antibody; Nucleoporin Nup96 antibody; CeNup96)] antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans npp-10 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Nup98 and Nup96 play a role in the bidirectional transport across the nucleoporin complex (NPC). Required for the nuclear import of hcp-4 during mitotic prophase, this step is essential for centrosome assembly and resolution. Regulates nucleoporin npp-5 localization to the nuclear membrane during interphase and to kinetochores during metaphase. Has a role in P granule integrity; may promote the 'liquid phase' of P granules by increasing the number of interacting RNA-protein complexes. Binds nos-2 mRNA, probably indirectly, and promotes its accumulation in P granules.
Subcellular Location
[Nuclear pore complex protein Nup98]: Cytoplasmic granule. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.; [Nuclear pore complex protein Nup96]: Nucleus, nuclear pore complex. Nucleus envelope. Chromosome.
Protein Families
Nucleoporin GLFG family
Database Links

KEGG: cel:CELE_ZK328.5

STRING: 6239.ZK328.5b

UniGene: Cel.17025

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