nusA Antibody

1. The results suggest that interaction between NusA and NusG could play various regulatory roles during transcription, including recruitment of NusG to RNAP, resynchronization of transcription: translation coupling, and modulation of termination efficiency. PMID: 27174929
2. The study showed that mutations in the NusA beta-flap domain specifically defective for N antitermination exhibited altered NusA-nascent RNA interaction and have widened RNA exit channel indicating an intricate role of flap domain in the antitermination. PMID: 25990722
3. Data suggest that RNA exit channel duplexes interact specifically with RNA polymerase and NusA and compete with RfaH to control clamp position. PMID: 24275665
4. Our results suggest that E. coli NusA can act as a protector to prevent protein aggregation under heat stress conditions in vitro and in the NusA-overexpressing strain. PMID: 23907089
5. Studies suggest that NusA, in addition to its known roles in transcription elongation and termination, is important for coordinating the cellular responses to DNA damage. PMID: 21326909
6. A missense nusA mutant xhibits a transcription termination-defective. PMID: 21602355
7. Data suggest that that NusA participates in an alternative class of TCR involved in the identification and removal of a class of lesion. PMID: 20696893
8. wild-type NusA function is required for stress-induced mutagenesis. This effect is unlikely to be due to defects in transcription of lac genes but rather is due to an inability to adapt and mutate in response to environmental stress. PMID: 20036541
9. Structural model of the carboxy-terminal domain of the transcription factor Escherichia coli NusA and its interaction sites with the protein N of bacteriophage lambda, and the carboxyl terminus of the E. coli RNA polymerase alpha subunit. PMID: 15987884
10. Titration experiments of the lambdaN(1-53)-nutBoxB RNA complex with NusA(339-495) revealed that ternary complex can be described in terms of two structurally independent binary interactions. PMID: 16584189
11. NusA is required for lambda-related phage 82 antiterminator Q(82) to construct a stable complex in which RNA-based termination mechanisms have restricted access to the emerging transcript. PMID: 17889665
12. findings show Rho termination, supported by NusA and NusG, is required to suppress the toxic activity of foreign genes PMID: 18487194
13. NusA binds only the nut regions of spacer sequence between boxA and boxB. PMID: 19515940

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KEGG: ecj:JW3138

STRING: 316385.ECDH10B_3343