sbr Antibody

Datasheet

Code	CSB-PA016218XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) sbr Polyclonal antibody

Uniprot No.

Q9U1H9

Target Names

sbr

Alternative Names

sbr antibody; nxf1 antibody; CG1664 antibody; Nuclear RNA export factor 1 antibody; Protein small bristles antibody; DmNXF1 antibody; Protein tip-associating antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) sbr protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm. In ovarian follicle cells, plays a role in transposable element silencing regulation by enabling the nuclear export of flamenco (flam) transcripts and subsequent piRNA biogenesis.

Gene References into Functions

we show that the Dm NXF1 (SBR) protein is present not only in the nucleus but also in the cytoplasm PMID: 27389771
data indicate that origin recognition complex depletion affects the Nxf1 association with the mRNP complex. PMID: 27016737
sbr12 deletion and short testis-specific isoforms of SBR cause male sterility. PMID: 26621383
For SBR protein we have shown the localization not only in the nucleus, but in the cytoplasm marking of characteristic cytoplasmic structures. PMID: 26349247
Dm NXF1 (SBR) protein is present in considerable amounts at all stages of the spermatogenesis. PMID: 20799623
Alternative transcripts expressed by small bristles, the Drosophila melanogaster nxf1 gene PMID: 20214956
demonstrate that the SBR(5) mutant allele is a deletion of 492 nucleotides that removes 146 amino acids in the mutant SBR(5) protein. PMID: 19779841
The frequency of abnormal chromosome sets in the offspring of male carriers of the sbr10 mutation is about two times higher than in the offspring of males without this mutation. PMID: 18069342

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Subcellular Location

Nucleus, nucleoplasm. Cytoplasm. Nucleus envelope.

Protein Families

NXF family

Tissue Specificity

Expressed ubiquitously.

Database Links

KEGG: dme:Dmel_CG1664

STRING: 7227.FBpp0073267

UniGene: Dm.1645

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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sbr Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background