Nqo2 Antibody

Code CSB-PA881303ZA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Nqo2 Polyclonal antibody
Uniprot No.
Target Names
Nqo2
Alternative Names
Nqo2 antibody; Nmor2 antibody; Ribosyldihydronicotinamide dehydrogenase [quinone] antibody; EC 1.10.5.1 antibody; NRH dehydrogenase [quinone] 2 antibody; NRH:quinone oxidoreductase 2 antibody; Quinone reductase 2 antibody; QR2 antibody
Raised in
Rabbit
Species Reactivity
Mus musculus
Immunogen
Recombinant Mus musculus Nqo2 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Gene References into Functions
  1. NQO2 stabilization of C/EBPalpha was independent of NQO1, even though both interacted with the same C/EBPa domain. PMID: 24142791
  2. Melatonin, acting at least partially via MT2 receptors, can regulate the redox status of quinone reductase II inhibited preadipocytes. PMID: 23554006
  3. role for NQO2 in protection against myelogenous hyperplasia and in metabolic activation of menadione, leading to hepatic toxicity PMID: 12351651
  4. These data establish dihydronicotinamide riboside:quinone reductase 2 (NQO2) as part of the MT3 binding site. PMID: 15581627
Subcellular Location
Cytoplasm.
Protein Families
NAD(P)H dehydrogenase (quinone) family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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