asrij Antibody

Code CSB-PA893362XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) asrij Polyclonal antibody
Uniprot No.
Target Names
asrij
Alternative Names
asrij antibody; CG13533 antibody; OCIA domain-containing protein 1 antibody; OCAD1 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) asrij protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Maintains stem cell potency. Involved in endocytic pathways that mediate signaling during hematopoiesis.
Gene References into Functions
  1. Results show that in addition to its requirement in hematopoiesis, the ARF1-Asrij axis can differentially regulate humoral immunity in Drosophila, most likely by virtue of its endosomal function. ARF1 and Asrij bring about differential endocytic modulation of immune pathways and their depletion leads to aberrant pathway activity and an immune imbalance. PMID: 28273919
  2. ARF1-Asrij endocytic axis modulates signals that govern hematopoietic development. PMID: 24707047
  3. a role for Asrij in causing increased Notch signaling thereby affecting hemocyte differentiation PMID: 22110713
  4. Drosophila asrij functions in the hematopoietic lineage PMID: 12690451
Subcellular Location
Endosome.
Protein Families
OCIAD1 family
Tissue Specificity
Expressed in all cells of the primary lymph gland lobe.
Database Links

KEGG: dme:Dmel_CG13533

STRING: 7227.FBpp0305129

UniGene: Dm.5105

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