dbt-1 Antibody

Code CSB-PA269103XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans dbt-1 Polyclonal antibody
Uniprot No.
Target Names
dbt-1
Alternative Names
dbt-1 antibody; ZK669.4 antibody; Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex antibody; mitochondrial antibody; EC 2.3.1.168 antibody; Branched-chain alpha-keto acid dehydrogenase complex component E2 antibody; Dihydrolipoamide branched-chain transacylase E2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans dbt-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component. Required for the catabolism of branched-chain amino acids and the subsequent synthesis of monomethyl branched-chain fatty acids, which are important for regulating postembryonic growth.
Subcellular Location
Mitochondrion matrix. Cytoplasm, cytosol. Cell projection, dendrite. Cell projection, cilium.
Protein Families
2-oxoacid dehydrogenase family
Tissue Specificity
Ubiquitously expressed.
Database Links

KEGG: cel:CELE_ZK669.4

STRING: 6239.ZK669.4.1

UniGene: Cel.6097

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