ninaE Antibody

1. Organisms use multiple strategies to maximize visual capabilities in different light conditions. Many invertebrates show a daily cycle of shedding the photoreceptor's rhabdomeric membranes at dawn and rebuilding these during the following night. We show here that the Aedes aegypti mosquito possesses two distinct light-driven cellular signaling processes for modulating rhodopsin content during this cycle. PMID: 27798185
2. Data show that site-directed mutagenesis of conserved residues has only modest effects on Rhodopsin 1 absorption. PMID: 26195627
3. Data indicate that mutations in Golgi SNARE protein gos28 lead to defective rhodopsin (Rh1) trafficking. PMID: 25261468
4. GPI biosynthesis is essential for rhodopsin sorting at the trans-Golgi network in Drosophila photoreceptors PMID: 23250212
5. Our results indicate that fatp promotes photoreceptor survival by regulating Rh1 abundance PMID: 22844251
6. Dominant rhodopsin (ninaE) mutants showed progressive age-dependent and light-independent loss of the deep pseudopupil. PMID: 22194648
7. Data propose that Rh1 function in promoting RTW morphogenesis is not only needed to sustain apical membrane delivery but is also required for proper rhabdomeric membrane endocytosis and turnover. PMID: 21486953
8. mutation of ninaE encoding Drosophila rhodopsin eliminates thermotactic discrimination in the comfortable temperature range; propose that rhodopsins represent a class of evolutionarily conserved GPCRs required for initiating thermosensory signaling PMID: 21393546
9. Data show tat mutant flies bearing certain ninaE alleles have dramatically reduced rhodopsin-1 protein levels. PMID: 19805114
10. expression of ceramidase facilitates the dissolution of incompletely formed and inappropriately located elements of rhabdomeric membranes in ninaE(I17) mutants lacking the G protein receptor Rh1 in R1-R6 photoreceptor cells PMID: 14769922
11. NinaE(pp100) represented the first rhodopsin mutation that stabilized rhodopsin-arrestin complex and led to elevated levels of G(q)alpha in the cytosol, which mediated a novel retinal degeneration pathway PMID: 15014127
12. We present evidence that the Drosophila GBS regulatory element (Glass-binding site), derived from the Rh1 rhodopsin gene, is able to drive in vivo eye-specific expression of a Ccwhite+ transgene in the Mediterranean fruitfly Ceratitis capitata. PMID: 16756553
13. Data show that the double Rhodopsin 1 (ninaE) and Rhodopsin mutant was not entrained to red light. PMID: 18766027

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KEGG: dme:Dmel_CG4550

STRING: 7227.FBpp0083266

UniGene: Dm.6744