Optix Antibody

Code CSB-PA836119XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Optix Polyclonal antibody
Uniprot No.
Target Names
Optix
Alternative Names
Optix antibody; opt antibody; Six3 antibody; CG18455 antibody; Protein Optix antibody; Homeobox protein SIX3 antibody; D-Six3 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Optix protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May be involved in head or eye development; development of the clypeolabrum and several head sensory organs.
Gene References into Functions
  1. Anteroposterior patterning of Drosophila ocelli requires an anti-repressor mechanism within the hh pathway mediated by the Six3 gene Optix. PMID: 26160900
  2. Sine oculis mutation within the Six domain does not abolish DNA-protein interactions, but alters co-factor binding specificity to resemble that of Optix PMID: 16125693
Subcellular Location
Nucleus.
Protein Families
SIX/Sine oculis homeobox family
Tissue Specificity
Expressed during early development of the head. First expressed in a band around the anterior end of stage 5 blastoderm embryo, at 93% to 85% egg length. By gastrula stage, site of expression shifts to the dorsal-anterior region. At stage 12, expression i
Database Links

KEGG: dme:Dmel_CG18455

STRING: 7227.FBpp0302920

UniGene: Dm.3727

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