orai-1 Antibody

Code CSB-PA632679XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans orai-1 Polyclonal antibody
Uniprot No.
Target Names
orai-1
Alternative Names
orai-1 antibody; C09F5.2 antibody; Protein orai antibody; Store-operated calcium channel antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans orai-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim-1. Required for Ca(2+) and IP3-dependent contractile activity of sheath cells and the spermatheca. Affects brood size and somatic cell function.
Gene References into Functions
  1. This review describes the role of Orai1 in Ca(2+) release activated Ca(2+) (CRAC) channel activity in worm gonad and intestine. PMID: 17376526
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Orai family
Tissue Specificity
Expressed in gonad sheath cells, hypodermis, intestine and spermatheca. Coexpressed with stim-1.
Database Links

STRING: 6239.C09F5.2a

UniGene: Cel.10849

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