ORC1B Antibody

Datasheet

Code	CSB-PA784025XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ORC1B Polyclonal antibody

Uniprot No.

Q9SU24

Target Names

ORC1B

Alternative Names

ORC1B antibody; UNE13 antibody; At4g12620 antibody; T1P17.210 antibody; Origin of replication complex subunit 1B antibody; AtORC1b antibody; Origin recognition complex 1b protein antibody; Protein UNFERTILIZED EMBRYO SAC 13 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana ORC1B protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Essential protein required for ovules fertilization. Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication. H3K4me3 effector that regulates positively the transcription of a subset of genes.

Gene References into Functions

Study reports on the structure of Arabidopsis ORC1b BAH-PHD cassette in complex with an unmodified H3(1-15) peptide. The structural and biochemical data showed a unique multivalent readout of unmodified H3 tail at H3R2, H3K4, and H3T3, providing a potential link between plant DNA replication and epigenetic regulation. PMID: 26876097
ORC1a and ORC1b are regulated by the E2F/DP family of transcription factors and AtORC1b promoter is active exclusively in proliferating cells PMID: 16179646

Subcellular Location

Nucleus.

Protein Families

ORC1 family

Tissue Specificity

Follow a cell-cycle regulation with a peak at the G1/S-phase. Mostly expressed in flower buds, and, to a lower exent, in roots, leaves and stems.

Database Links

KEGG: ath:AT4G12620

STRING: 3702.AT4G12620.1

UniGene: At.48852

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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