Tcs3 Antibody

Code CSB-PA894740XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Tcs3 Polyclonal antibody
Uniprot No.
Target Names
Tcs3
Alternative Names
Tcs3 antibody; CG4933 antibody; Probable tRNA N6-adenosine threonylcarbamoyltransferase antibody; EC 2.3.1.234 antibody; N6-L-threonylcarbamoyladenine synthase antibody; t(6)A synthase antibody; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Tcs3 antibody; tRNA threonylcarbamoyladenosine biosynthesis protein Tcs3 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Tcs3 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Gene References into Functions
  1. Drosophila kae1 and its partners are core factors in t6A biogenesis. PMID: 26516084
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
KAE1 / TsaD family
Database Links

KEGG: dme:Dmel_CG4933

STRING: 7227.FBpp0075139

UniGene: Dm.31123

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