osm-1 Antibody

Code CSB-PA635492XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans osm-1 Polyclonal antibody
Uniprot No.
Target Names
osm-1
Alternative Names
osm-1 antibody; T27B1.1 antibody; Intraflagellar transport protein osm-1 antibody; Osmotic avoidance abnormal protein 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans osm-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for the maintenance and formation of chemosensory cilia that detect chemosensory cues.
Gene References into Functions
  1. The cloning of osm-1 gene, this gene affects chemotaxis and are reqiured for intraflgellar transport. PMID: 16648645
Subcellular Location
Cell projection, cilium. Note=Emerges from the transition zones and move in a bidirectional fashion along the sensory cilia, displaying anterograde movement from the transition zone toward the tip of the ciliary axoneme and retrograde movement from the cilium tip back toward the transition zone.
Protein Families
IFT172 family
Tissue Specificity
Expressed in amphid and phasmid chemosensory neurons, where it appears to concentrate at the base of the transition zones, which correspond to the basal bodies of motile and sensory cilia. Moves in the retrograde direction along cilia and dendrites, sugge
Database Links

KEGG: cel:CELE_T27B1.1

STRING: 6239.T27B1.1

UniGene: Cel.253

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