otu Antibody

Code CSB-PA320746XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) otu Polyclonal antibody
Uniprot No.
Target Names
otu
Alternative Names
otu antibody; CG12743 antibody; Protein ovarian tumor locus antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) otu protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Essential for female fertility; germ cell division and differentiation.
Gene References into Functions
  1. There is an evolutionary loss of activity in de-ubiquitylating enzymes of the OTU family, OTUD4, otu, and CG3251. PMID: 26588485
  2. ovarian tumour has a specific role in the developmentally regulated accumulation of sex-lehtal protein within the cytoplasm and nucleus. PMID: 12000643
  3. an examination of chromosomes in otu mutants of Drosophila melanogaster in ovarian nurse cells PMID: 14707346
  4. Data show that Squid (Sqd) interacts with Hrb27C, and that Ovarian tumor (Otu) cooperates with Hrb27C and Sqd in the oocyte to mediate proper gurken (grk) localization. PMID: 15056611
  5. Mutations in ovarian tumor (otu) interfere with both Sxl germline functions. PMID: 19171941

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Subcellular Location
Cytoplasm.
Tissue Specificity
Expressed in both oocyte and nurse cells of the germarium.
Database Links

KEGG: dme:Dmel_CG12743

STRING: 7227.FBpp0071181

UniGene: Dm.7029

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