oxyR Antibody

Code CSB-PA359813XA01FQR
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Product Details

Full Product Name
Rabbit anti-Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) oxyR Polyclonal antibody
Uniprot No.
Target Names
oxyR
Alternative Names
oxyR antibody; c4922 antibody; Hydrogen peroxide-inducible genes activator antibody; Morphology and auto-aggregation control protein antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Immunogen
Recombinant Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) oxyR protein
Immunogen Species
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto-aggregation ability.
Database Links

KEGG: ecc:c4922

STRING: 199310.c4922

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