KAPP Antibody

Datasheet

Code	CSB-PA332802XA01DOA
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Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KAPP Polyclonal antibody

Uniprot No.

P46014

Target Names

KAPP

Alternative Names

KAPP antibody; RAG1 antibody; At5g19280 antibody; F7K24.30 antibody; T24G5.3 antibody; Protein phosphatase 2C 70 antibody; AtPP2C70 antibody; EC 3.1.3.16 antibody; Kinase-associated protein phosphatase antibody; Protein ROOT ATTENUATED GROWTH 1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana KAPP protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Dephosphorylates the Ser/Thr receptor-like kinase RLK5. May function as a signaling component in a pathway involving RLK5. Binds and dephosphorylates CLAVATA1 (CLV1). Functions as a negative regulator of the CLV1 signaling in plant development. Dephosphorylates SERK1 receptor kinase on threonine residues in the A-loop. Dephosphorylation of SERK1 controls SERK1 internalization. Component of a signaling pathway which mediates adaptation to NaCl stress. Is not a component of the SALT OVERLY SENSITIVE (SOS) pathway.

Gene References into Functions

Phosphopeptide binding introduces conformational fluctuations to residues of the long recognition loop of the kinase-interacting-forkhead-associated domain of KAPP; rigidity of this domain appears to couple as a whole to phosphothreonine peptide binding. PMID: 16042389
The crystal structure of the binary complex of Ca-SOS3 with the C-terminal regulatory moiety of SOS2 resolves central questions regarding the dual function of SOS2 as a kinase and a phosphatase-binding protein. PMID: 17499048
These results implicate KAPP as a functional component of the RLK signaling pathway, which also mediates adaptation to Na(+) stress. PMID: 18162596

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity

Expressed in all tissues examined.

Database Links

KEGG: ath:AT5G19280

STRING: 3702.AT5G19280.2

UniGene: At.10199

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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KAPP Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background