pac-1 Antibody

Code CSB-PA327307XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans pac-1 Polyclonal antibody
Uniprot No.
Target Names
pac-1
Alternative Names
pac-1 antibody; gap antibody; C04D8.1GTPase-activating protein pac-1 antibody; GTPase-activating protein GAP antibody; CeGAP antibody; Protein par-6-at-contacts antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans pac-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
GTPase-activating protein for members of the Rho subfamily including Rac1, RhoA and cdc42 and other Ras-related subfamilies including let-60. Mediates radial (inner-outer) polarity and gastrulation by excluding par-6 from contacted cell surfaces; acts by inactivating cdc42 at inner cell surfaces which limits active cdc42 to outer cell surfaces devoid of cell-cell contacts, where cdc42 can bind and recruit par-6. Required for blastomere polarization.
Subcellular Location
Cytoplasm. Cell junction. Cell junction, adherens junction.
Database Links

STRING: 6239.C04D8.1c

UniGene: Cel.17260

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