pain Antibody

1. Recent work has uncovered the painless, mediating fly thermosensation. PMID: 25616212
2. For the regulation of sexual receptivity through Pain TRP channels. PMID: 24505416
3. in the case of Painless, ankryin repeats are important for thermal nociception but not for mechanical nociception PMID: 22295071
4. results indicate that functions of painless in the adult central nervous system of Drosophila include modulation of olfactory processing and inhibition of male-male courtship behavior PMID: 22073144
5. Painless constitutes part of a mechanosensitive pathway that adjusts cardiac muscle activity to mechanical constraints. PMID: 20824071
6. A transient receptor potential (TRP) channel family member, painless, plays a role in low- and high-temperature responses. PMID: 14585595
7. The stinging sensation of isothiocyanate, the pungent ingredient of wasabi, is caused by activation of an evolutionarily conserved molecular pathway that is also used for nociception. PMID: 16647259
8. Abnormal nociceptive behavior of a mutant, painless, indicates that painless, a gene essential for nociception in Drosophila larvae, is also required for thermal nociception in adult flies. PMID: 17081265
9. We found that fructose potently elicited larval food-averse behaviors, and painless (pain), a transient receptor potential channel that is responsive to noxious stimuli, was required for the fructose response. PMID: 18469811
10. Painless protein is a direct sensor for noxious heat in Drosophila; Painless mediates a robust intracellular divalent calcium ion increase during heating as well as heat-evoked inward currents in whole-cell patch-clamp mode. PMID: 18829951
11. Our results suggest that Pain TRP channels expressed in cholinergic and/or GABAergic neurons are involved in female sexual receptivity. PMID: 19531155

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KEGG: dme:Dmel_CG15860

STRING: 7227.FBpp0072323

UniGene: Dm.14984