Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PANS1 Polyclonal antibody

Uniprot No.

Q9LJG6

Target Names

PANS1

Alternative Names

PANS1 antibody; CMR1 antibody; At3g14190 antibody; Protein PATRONUS 1 antibody; Protein COPPER MODIFIED RESISTANCE 1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana PANS1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Required for the maintenance of centromeric cohesion during interkinesis, until meiosis II. Required for regular configuration and segregation of sister chromatids in meiosis II. Also required for centromere cohesion during meiosis I. Involved in spindle organization at the end of telophase I and in meiosis II. Required to prevent precocious release of pericentromeric cohesins during meiosis, but not for cohesion establishment and monopolar orientation of kinetochores at meiosis I. Involved also in somatic development. Regulates mitotic cell division and ploidy stability in somatic cell types. May be involved in the organization of microtubules dynamics. Involved in abiotic stresses and mono- or divalent ions tolerance and may play a role in maintaining meristematic activity under saline conditions. PANS1 and GIG1 are part of a network linking centromere cohesion and cell cycle progression through control of APC/C activity. Regulates the number of dividing cells in root meristem and is necessary for the anaphase onset control through an APC/C-mediated pathway. Involved in maintaining correct chromosome arm cohesion under stress conditions.

Gene References into Functions

Likely, CMR1/PANS1 coordinates mitotic cell cycle progression by acting as an anaphase-promoting complex/cyclosome (APC/C) inhibitor and plays a key role in growth adaptation to stress. PMID: 26261921
PANS1 is expressed mainly in meiosis I where it has an important function; PANS1 and OSD1 are part of a network linking centromere cohesion and cell cycle progression through control of Anaphase Promoting Complex/Cyclosome (APC/C) activity. PMID: 26272661
preserves ploidy stability during meiosis and mitosis PMID: 24506176

Subcellular Location

Nucleus. Cytoplasm.

Tissue Specificity

Expressed in somatic and reproductive tissues. Expressed in inflorescence, young buds, roots and basal portion of young leaves. Expressed in proliferating cells such as apical meristems of roots and shoots, expanding cotyledons and leaves, root vascular t

Database Links

KEGG: ath:AT3G14190

STRING: 3702.AT3G14190.1

UniGene: At.39277

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PANS1 Antibody

Product Details

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Target Background