PARN Antibody

Code CSB-PA885340XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PARN Polyclonal antibody
Uniprot No.
Target Names
PARN
Alternative Names
PARN antibody; AHG2 antibody; At1g55870 antibody; F14J16.11Poly(A)-specific ribonuclease PARN antibody; EC 3.1.13.4 antibody; Polyadenylate-specific ribonuclease antibody; AtPARN antibody; Protein ABA hypersensitive germination 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana PARN protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. Essential for early development, possibly by participating in silencing certain maternal mRNAs translationally. May have a pivotal role in stress response.
Gene References into Functions
  1. AHG2 and AGS1 constitute a regulatory system that controls mitochondrial mRNA poly(A) status in Arabidopsis. PMID: 23912222
  2. A partial defect of AHG2/PARN perturbs mitochondrial function independently in addition to the abscisic acid and salicylic acid responses. PMID: 19892832
  3. AHG2 encodes a poly(A)-specific ribonuclease (AtPARN)that is presumed to function in mRNA degradation. Both upregulation and downregulation of gene expression by AtPARN are crucial for proper ABA, salicylic acid and stress responses. [AHG2] PMID: 16359390
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
CAF1 family
Tissue Specificity
Widely expressed. Expressed in roots, stems, leaves and flowers.
Database Links

KEGG: ath:AT1G55870

STRING: 3702.AT1G55870.1

UniGene: At.49981

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