pat-12 Antibody

Code CSB-PA285289XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans pat-12 Polyclonal antibody
Uniprot No.
Target Names
pat-12
Alternative Names
pat-12 antibody; T17H7.4Protein pat-12 antibody; Paralyzed arrest at two-fold 12 protein antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans pat-12 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for embryonic morphology and development. Plays both a functional and a structural role in the maintenance and probably biogenesis of fibrous organelles, a hemidesomosome-like junction structure, which ensures muscle stability and muscle connection to the external cuticle.
Gene References into Functions
  1. PAT-12 defines a novel component of C. elegans hemidesmosomes, which is required for maintaining their integrity PMID: 21130760
Subcellular Location
[Isoform a]: Apical cell membrane; Peripheral membrane protein. Basal cell membrane; Peripheral membrane protein. Cytoplasm. Cell junction, hemidesmosome.; [Isoform e]: Cell membrane.; [Isoform f]: Cell membrane.; [Isoform i]: Cell membrane.; [Isoform j]: Basal cell membrane. Apical cell membrane. Cytoplasm. Cell junction, hemidesmosome.; [Isoform k]: Cell junction, hemidesmosome. Cytoplasm, cytoskeleton.
Tissue Specificity
Isoform a: Expressed in the uterus, the vulva, the rectum, mechanosensory neurons and in head and tail neurons. Isoform e: Expressed in spermatheca and weakly in the vulva. Isoform f: Expressed in spermatheca and weakly in the vulva. Isoform i: Expressed
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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