PCNA2 Antibody

Code CSB-PA972167XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PCNA2 Polyclonal antibody
Uniprot No.
Target Names
PCNA2
Alternative Names
PCNA2 antibody; At2g29570 antibody; F16P2.5 antibody; Proliferating cell nuclear antigen 2 antibody; PCNA 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana PCNA2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. May be involved in UV resistance.
Gene References into Functions
  1. Arabidopsis PCNA1 and PCNA2 differ in their efficiency for ubiquitination and sumoylation, leading to their differential responses to DNA damage in yeast cells. PMID: 25728088
  2. PCNA1 and PCNA2 may cooperate in planta by forming homo- and heterotrimeric rings. PMID: 23656863
  3. PCNA2 but not PCNA1 increases the selectivity for dCTP incorporation opposite 8-Oxo-G by DNA Pol lambda. PMID: 21325140
  4. AtPolH confers UV resistance by interacting with PNCA2 and catalyzing translesion synthesis. PMID: 18494853
  5. atomic resolution crystal structures of the PCNA1 and PCNA2 complexed with the C-terminal segment of human p21; structures demonstrated that PCNA1 & 2 adopt identical architectures PMID: 19388052

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Subcellular Location
Nucleus.
Protein Families
PCNA family
Database Links

KEGG: ath:AT2G29570

STRING: 3702.AT2G29570.1

UniGene: At.23904

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