Pxt Antibody

Code CSB-PA893267XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Pxt Polyclonal antibody
Uniprot No.
Target Names
Pxt
Alternative Names
Pxt antibody; CG7660 antibody; Chorion peroxidase antibody; EC 1.11.1.7 antibody; Peroxinectin-related protein antibody; Dpxt antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Pxt protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for ovarian follicle maturation. Involved in the formation of a rigid and insoluble egg chorion by catalyzing chorion protein cross-linking through dityrosine formation and phenol oxidase-catalyzed chorion melanization.
Gene References into Functions
  1. Mutations in pxt, encoding a putative Drosophila cyclooxygenase, cause many transcripts to begin expression prematurely, and are associated with eggshell defects. PMID: 21637834
  2. Dpxt function is restricted to the early stages of fly development PMID: 12459925
  3. Drosophila ovarian follicle maturation requires cyclooxygenase-like activity, supplied by peroxidase PXT. PMID: 18216169
Subcellular Location
Secreted. Note=In the chorion layer of the mature eggs.
Protein Families
Peroxidase family, XPO subfamily
Tissue Specificity
Expressed at low levels in the germarium and early follicles. Expression becomes progressively stronger during vitellogenesis, and is highly expressed in germ cells and somatic cells. A subset of follicle cells, termed border cells (BC), exhibit a high le
Database Links

KEGG: dme:Dmel_CG7660

STRING: 7227.FBpp0082932

UniGene: Dm.19352

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