PEX11 Antibody

Code CSB-PA621489XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX11 Polyclonal antibody
Uniprot No.
Target Names
PEX11
Alternative Names
PEX11 antibody; PMP24 antibody; PMP27 antibody; YOL147C antibody; O0454 antibody; Peroxisomal membrane protein PMP27 antibody; Peroxin-11 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX11 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in peroxisomal proliferation. Promotes peroxisome division and biogenesis.
Gene References into Functions
  1. Data indicate that phosphorylation of peroxisomal membrane protein 27 (Pex11) may regulate peroxisomal beta-oxidation. PMID: 26597702
  2. The membrane remodeling protein Pex11p activates the GTPase Dnm1p during peroxisomal fission. PMID: 25941407
  3. Pex11 and Mdm34 physically interact and that Pex11 plays a role in establishing the contact sites between peroxisomes and mitochondria through the ERMES complex. PMID: 25769804
  4. ScPex11p promotes the proliferation of peroxisomes already present in the cell, ScPex25p initiates remodeling at the peroxisomal membrane and ScPex27p acts to counter this activity. PMID: 21951626
  5. report the reversible phosphorylation of Pex11p in response to nutritional cues and delineate a mechanism for phosphorylation-dependent activation of Pex11p and peroxisome proliferation PMID: 20028986

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Subcellular Location
Peroxisome membrane; Peripheral membrane protein.
Protein Families
Peroxin-11 family
Database Links

KEGG: sce:YOL147C

STRING: 4932.YOL147C

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