PEX21 Antibody

Code CSB-PA342269XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX21 Polyclonal antibody
Uniprot No.
Target Names
PEX21
Alternative Names
PEX21 antibody; YGR239C antibody; G8593 antibody; Peroxisomal membrane protein PEX21 antibody; Peroxin-21 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX21 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in peroxisome biogenesis and the import of peroxisomal matrix proteins that contain the peroxisomal targeting sequence PTS2. Required for peroxisomal targeting of PEX7 and growth on oleate. Acts as an activator of the seryl-tRNA synthetase SES1 by increasing its binding to tRNA.
Gene References into Functions
  1. Data revealed that both PTS-receptors as well as the auxiliary proteins Pex18p and Pex21p are neither required for Pex8p association with the importomer nor for its function as an organizer of the peroxisomal protein import machinery. PMID: 20655618
  2. Pex21p does not directly bind tRNA, nor does it possess tRNA-binding motif, but it participates in formation of specific ternary complex with seryl-tRNA synthetase & tRNA(Ser), strengthening interaction of seryl-tRNA synthetase with its cognate tRNA(Ser) PMID: 17451428
Subcellular Location
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Families
Peroxin-21 family
Database Links

KEGG: sce:YGR239C

STRING: 4932.YGR239C

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