PEX22 Antibody

Code CSB-PA336615XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX22 Polyclonal antibody
Uniprot No.
Target Names
PEX22
Alternative Names
PEX22; YAL055W; Peroxisome assembly protein 22; Peroxin-22
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX22 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in peroxisome biogenesis.
Gene References into Functions
  1. mutation, causing Pex22p dysfunction, was sufficient to confer increased malate productivity and dimethyl succinate sensitivity to yeast cells PMID: 28919252
  2. The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor (Pex5). PMID: 25162638
  3. The Pex4p:Pex22p assembly, and not Pex4p alone, functions as the E2 enzyme required for Pex5p ubiquitination. This is a novel mechanism of E2 enzyme regulation. PMID: 22085930
  4. The N-domain of Pex22p can functionally replace the Pex3p N-domain in targeting and peroxisome formation. PMID: 19017643
Subcellular Location
Peroxisome membrane; Single-pass membrane protein.
Protein Families
Peroxin-22 family
Database Links

KEGG: sce:YAL055W

STRING: 4932.YAL055W

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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