PEX6 Antibody

Code CSB-PA330282XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX6 Polyclonal antibody
Uniprot No.
Target Names
PEX6
Alternative Names
PEX6 antibody; PAS8 antibody; YNL329C antibody; N0310 antibody; Peroxisomal ATPase PEX6 antibody; Peroxin-6 antibody; Peroxisomal assembly protein 8 antibody; Peroxisome biosynthesis protein PAS8 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PEX6 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the peroxisomal protein import machinery. Together with PEX1, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1) import receptor PEX5 from the peroxisomal membrane to the cytosol, where it is then available for another round of protein import into the organelle.
Gene References into Functions
  1. Pex6 protein mediates the ATP-dependent dislocation of the peroxisomal targeting signal-1 (PTS1) receptor from the peroxisomal membrane to the cytosol. PMID: 16007078
  2. PEX6 has a role in suppression of aging defects in mitochondria PMID: 17465979
  3. These results provide evidence that in a deletion of PEX6 increases acetic acid-mediated necrotic cell death in Saccharomyces cerevisiae. PMID: 18656474
Subcellular Location
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Families
AAA ATPase family
Database Links

KEGG: sce:YNL329C

STRING: 4932.YNL329C

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