pgtE Antibody

Code CSB-PA361739XA01SXB
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Product Details

Full Product Name
Rabbit anti-Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) pgtE Polyclonal antibody
Uniprot No.
Target Names
pgtE
Alternative Names
pgtE antibody; prtA antibody; STM2395 antibody; Outer membrane protease E antibody; E protein antibody; EC 3.4.23.- antibody
Raised in
Rabbit
Species Reactivity
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Immunogen
Recombinant Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) pgtE protein
Immunogen Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Protease that can cleave T7 RNA polymerase. Specific for paired basic residues.
Gene References into Functions
  1. intracellular enhancement of PgtE activity in Salmonella may promote macrophage-associated proteolysis and cellular migration by altering the balance between host plasmin and alpha(2)-antiplasmin PMID: 15760453
  2. Our results indicate that PgtE and Pla have diverged in substrate specificity, and suggest that Salmonella PgtE has evolved to functionally mimic mammalian matrix metalloproteinases PMID: 17888724
Subcellular Location
Cell outer membrane; Multi-pass membrane protein.
Protein Families
Peptidase A26 family
Database Links

KEGG: stm:STM2395

STRING: 99287.STM2395

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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