phb-1 Antibody

Code CSB-PA861054XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans phb-1 Polyclonal antibody
Uniprot No.
Target Names
phb-1
Alternative Names
phb-1 antibody; Y37E3.9 antibody; Mitochondrial prohibitin complex protein 1 antibody; Prohibitin-1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans phb-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
PHB proteins are essential during embryonic development and are required for somatic and germline differentiation in the larval gonad. A deficiency in PHB proteins results in altered mitochondrial biogenesis in body wall muscle cells.
Gene References into Functions
  1. The p38MAPK/ATF-7 immune pathway is triggered by mitochondrial complex I dysfunction. PMID: 27545884
  2. role in embryonic viability and germline function PMID: 12794069
  3. mitochondrial prohibitin complex promotes longevity by modulating mitochondrial function and fat metabolism in the nematode Caenorhabditis elegans PMID: 19812672
Subcellular Location
Mitochondrion inner membrane.
Protein Families
Prohibitin family
Database Links

KEGG: cel:CELE_Y37E3.9

STRING: 6239.Y37E3.9.1

UniGene: Cel.6379

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