PHO4 Antibody

1. Pho85 and Pho4 regulated CLN2 expression under alkaline condition. PMID: 25582350
2. Subsequent in-depth analysis of the inducible PHO5 gene reveals that topoisomerases are essential for binding of the Pho4p transcription factor to the PHO5 promoter, which is required for promoter nucleosome removal during activation. PMID: 23284296
3. The authors postulate that RPL12 has an extra-ribosomal function in modulating the transcription of genes that need Pho4p activation. PMID: 21469193
4. three transcriptional outputs can be generated by a pathway whose regulation is controlled by one kinase, Pho80-Pho85, and one transcription factor, Pho4 PMID: 14624238
5. These data establish a G1 checkpoint adaptation pathway where Pho85 mediates Pho4 downregulation and Sic1 degradation to release Cdc28 activity and promote onset of S phase. PMID: 16964260
6. Pho4 binding to the SNZ1/SNO1 promoter is accompanied by alterations in chromatin structure, and Rpd3 histone deacetylase is required for the proper timing of SNZ1/SNO1 expression, while Asf1 histone chaperone is indispensable for their expression. PMID: 18408055
7. Pho4 activates some stress response genes, is required for G1 arrest caused by DNA damage, and is present in the nucleus even under high-Pi conditions to activate or repress transcription. PMID: 19108609

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KEGG: sce:YFR034C

STRING: 4932.YFR034C