PHO84 Antibody

1. The phosphate-binding site residues were shown to be well conserved between all the plant PHT1 proteins and Saccharomyces cerevisiae PHO84. PMID: 27911737
2. Molecular dynamics simulations of Pho84 in which a residue adjacent to Tyr(179), Asp(178), is protonated revealed a conformational change in Pho84 from an open, inward-facing state to an occluded state. PMID: 27875295
3. The role of Pho84 in phosphate signalling is discussed. [review] PMID: 24845516
4. PHO84 silencing uses antisense transcription via the promoter rather than the static accumulation of antisense RNAs at the repressed gene. PHO84 antisense RNA acts as a bimodal switch. PMID: 23770821
5. trace levels of arsenate (70 ppb), the phosphate reduced the initial rate of uptake, but not the total amount removed. PHO84 mRNA levels were nearly 30 times higher in the engineered strains relative to the control strains PMID: 22628173
6. Asp(358) (helix 7) and Lys(492) (helix 11) are critical for the transport function, and might be part of the putative substrate-binding pocket of Pho84. PMID: 22587366
7. Pho84 functions as a sensor for glycerol-3-phosphate in Protein Kinase A signaling. PMID: 20133652
8. We propose that Rpd3p has a negative role in the regulation of Pho84p endocytosis. PMID: 16087743
9. A natural coding-region polymorphism in the inorganic phosphate transporter PHO84 underlies sensitivity to two polychlorinated phenols that uncouple oxidative phosphorylation. PMID: 17334364
10. Chromatin cofactor requirements were determined by intrinsic nucleosome stabilities rather than correlated to promoter strength. PMID: 19307305
11. Pho84-mediated activation of the PKA pathway is responsible for its own downregulation by phosphorylation, ubiquination, internalization, and vacuolar breakdown. PMID: 19348508

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KEGG: sce:YML123C

STRING: 4932.YML123C