pid-1 Antibody

Code CSB-PA787791XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans pid-1 Polyclonal antibody
Uniprot No.
Target Names
pid-1
Alternative Names
pid-1 antibody; F18A1.8 antibody; 21U-RNA biogenesis factor pid-1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans pid-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the pid-1 variant of the PETISCO complex which is required for the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs). Within the complex acts as an adapter which binds to the complex via erh-2. Involved in the biogenesis of 21U-RNAs which guide the piwi protein prg-1 to its DNA targets for silencing. Plays a role in small RNA-directed transgenerational epigenetic inheritance.
Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Tissue Specificity
Expressed predominantly in the germline (at protein level).
Database Links

KEGG: cel:CELE_F18A1.8

STRING: 6239.F18A1.8

UniGene: Cel.15377

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