PIP1-2 Antibody

Code CSB-PA651521XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PIP1-2 Polyclonal antibody
Uniprot No.
Target Names
PIP1-2
Alternative Names
PIP1-2 antibody; PIP1B antibody; TMPA antibody; At2g45960 antibody; F4I18.6 antibody; Aquaporin PIP1-2 antibody; AtPIP1;2 antibody; Plasma membrane intrinsic protein 1b antibody; PIP1b antibody; Transmembrane protein A antibody; AthH2 antibody; TMP-A antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana PIP1-2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Water channel required to facilitate the transport of water across cell membrane. Essential for the water permeability of the plasma membrane and for the morphology of the root system. Its function is impaired by Hg(2+). Inhibited by cytosolic acidosis which occurs during anoxia in roots.
Gene References into Functions
  1. Results identified 2 members of the receptor-like kinase (RLK) family (RKL1 (At1g48480) and Feronia (At3g51550)) differentially modulate PIP1;2 and PIP2;1 activity through distinct molecular mechanisms. PMID: 27609422
  2. The AtPIP1;2 function in plant physiology is to facilitate CO2 diffusion. PMID: 25850563
  3. The AtPIP1;2 gene product limits CO diffusion and photosynthesis in leaves. PMID: 21564354
  4. Cellular CO(2) transport was not limited by unstirred layer effects but was dependent on the expression of the aquaporin AtPIP1;2. PMID: 22150826
  5. The expression of both AtPIP1;2 and AtPIP2;1 oscillated with the circadian rhythm under low light conditions in wild-type seedlings, but not in the elf3 mutant. PMID: 21186174
  6. AtPIP1;2 significantly contributes to the hydraulic conductivity of both roots and rosette. PMID: 20034965

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
MIP/aquaporin (TC 1.A.8) family, PIP (TC 1.A.8.11) subfamily
Tissue Specificity
Widely expressed. Expressed in roots and above ground.
Database Links

KEGG: ath:AT2G45960

UniGene: At.20518

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