PKD2 Antibody

Code CSB-PA905960XA01DIL
Product Type Polyclonal Antibody
Uniprot No. Q6IVV8
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) PKD2 protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) pkd2
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names pkd2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Functions as non-selective cation channel (By similarity). Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades
Subcellular Location Basolateral cell membrane, Multi-pass membrane protein, Cell membrane, sarcolemma, Cytoplasm, myofibril, sarcomere, Sarcoplasmic reticulum membrane, Apical cell membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane, Multi-pass membrane protein, Cell projection, cilium, Cytoplasm, cytoskeleton, cilium basal body, Cytoplasmic vesicle membrane
Protein Families Polycystin family
Tissue Specificity Detected along cilia and at the cilium basal body in Kupffer's vesicle at the 10 somite stage (PubMed:26432887). Detected in heart at 48hpf (PubMed:23376035). Detected in muscle and pronephric kidney at 48 hpf (PubMed:16943304). Detected on trunk muscle s
Database Links

KEGG: dre:432387

STRING: 7955.ENSDARP00000027024

UniGene: Dr.92211

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