atgl-1 Antibody

Code CSB-PA606131XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans atgl-1 Polyclonal antibody
Uniprot No.
Target Names
atgl-1
Alternative Names
atgl-1 antibody; C05D11.7 antibody; Patanin-like phospholipase domain-containing protein antibody; EC 3.1.1.3 antibody; Adipose triglyceride lipase 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans atgl-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Component of a feedback loop involving atfs-1, atgl-1 and hlh-11. Promotes fat oxidation in response to mitochondrial stress. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion. Acts coordinately with lid-1 within the lipolytic cascade to distribute stored energy to tissues. Together with lipid droplet protein cgi-58, regulates lipid reserves as well as lipid droplet size and localization during the dauer phase in response to phosphorylation by ampk. May regulate serotonin-mediated lipolysis in metabolic tissues.
Subcellular Location
Lipid droplet. Cell membrane; Single-pass type II membrane protein. Cytoplasm.
Tissue Specificity
Expressed in the hypodermis. Expressed in the intestine (at protein level).
Database Links

STRING: 6239.C05D11.7b.2

UniGene: Cel.8627

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