PlexB Antibody

1. semaphorin 2b is a target-derived signal that acts upon presynaptic plexin B receptors to mediate the retrograde, homeostatic control of presynaptic neurotransmitter release at the neuromuscular junction in Drosophila; Sema2b-PlexB signalling regulates presynaptic homeostatic plasticity through the cytoplasmic protein Mical and the oxoreductase-dependent control of presynaptic actin PMID: 28953869
2. This study demonstrated that the evidence that PlexB mediates not only Sema-2a/2b-dependent guidance functions, but also Sema-2a/2b-independent target recognition in establishing the segmental nerve a motor axon pathway. PMID: 27637927
3. PlexinA functions to suppress excessive axonal branches and synapses and PlexinB facilitates axonal growth. PMID: 21489263
4. In the absence of PlexB, chordotonal afferent connectivity within the CNS is severely disrupted, resulting in specific larval behavioral deficits. PMID: 21521614
5. nervy regulates repulsive axon guidance by linking the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) to the Semaphorin 1a receptor Plexin A PMID: 14976319
6. Semaphorin 2a secreted by oenocytes signals through plexin B and plexin A to guide sensory axons in the Drosophila embryo, with PlexB play the major signaling role. PMID: 17109838

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KEGG: dme:Dmel_CG17245

STRING: 7227.FBpp0300616

UniGene: Dm.1700