poc1b Antibody

Code CSB-PA026040XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) poc1b Polyclonal antibody
Uniprot No.
Target Names
poc1b
Alternative Names
poc1b antibody; tuwd12 antibody; wdr51b antibody; si:dkey-164B12.2 antibody; POC1 centriolar protein homolog B antibody; WD repeat domain 51B antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) poc1b protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control.
Gene References into Functions
  1. data suggest that poc1b is required for normal development and ciliogenesis of retinal photoreceptor sensory cilia and other cilia PMID: 26188096
  2. Poc1B knockdown causes ciliary defects & morphological phenotype consistent with ciliopathies; Poc1 provides link between assembly & stability of centrioles for ciliary-based motility in Tetrahymena & cilia formation & function in D rerio & humans PMID: 20008567
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein Families
WD repeat POC1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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