POF1 Antibody

Code CSB-PA340711XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) POF1 Polyclonal antibody
Uniprot No.
Target Names
POF1
Alternative Names
POF1 antibody; YCL047C antibody; YCL47C antibody; Nicotinamide mononucleotide adenylyltransferase antibody; NMN adenylyltransferase antibody; NMNAT antibody; EC 2.7.7.1 antibody; NMN-specific adenylyltransferase antibody; Promoter of filamentation protein 1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) POF1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Involved in the salvage pathway for NAD(+) biosynthesis via NMN. Involved in the filamentation pathway. Suppresses the filamentation defect of a KSS1 deletion.
Gene References into Functions
  1. Yeast cells lacking YCL047C/POF1 release considerably more nicotinamide riboside compared with wild type, suggesting that POF1 plays an important role in NR/NAD(+) metabolism. PMID: 24759102
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Eukaryotic NMN adenylyltransferase family, POF1 subfamily
Database Links

KEGG: sce:YCL047C

STRING: 4932.YCL047C

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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