gag-pol Antibody

Code CSB-PA365916XA01RHO
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Rous sarcoma virus (strain Prague C) (RSV-PrC) gag-pol Polyclonal antibody
Uniprot No.
Target Names
gag-pol
Alternative Names
gag-pol antibody; Gag-Pol polyprotein [Cleaved into: Matrix protein p19; p2A; p2B; p10; Capsid protein p27 antibody; alternate cleaved 1; Capsid protein p27 antibody; alternate cleaved 2; Spacer peptide antibody; SP antibody; p3); Nucleocapsid protein p12; Protease p15 antibody; EC 3.4.23.-); Reverse transcriptase beta-subunit antibody; RT-beta); Reverse transcriptase alpha-subunit antibody; RT-alpha antibody; EC 2.7.7.49 antibody; EC 2.7.7.7 antibody; EC 3.1.26.4); Integrase antibody; IN antibody; EC 2.7.7.- antibody; EC 3.1.-.- antibody; pp32); p4] antibody
Raised in
Rabbit
Species Reactivity
Rous sarcoma virus (strain Prague C) (RSV-PrC)
Immunogen
Recombinant Rous sarcoma virus (strain Prague C) (RSV-PrC) gag-pol protein
Immunogen Species
Rous sarcoma virus (strain Prague C) (RSV-PrC)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Capsid protein p27: Self-associates to form the irregular polyhedron core composed of hexamers and pentamers, that encapsulates the genomic RNA-nucleocapsid complex. Assembles as a tube in vitro.; Plays a role in the oligomerization of the Gag polyprotein and in the stabilization of the immature particle. Essential layering element during tube assembly.; Binds strongly to viral nucleic acids and promote their aggregation. Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs.; The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell.; Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This recombination event is an essential step in the viral replication cycle. Has a strong preference for using the 3'-OH at the viral DNA end as a nucleophile.
Gene References into Functions
  1. crystal structure of the three-domain integrase from Rous sarcoma virus in complex with viral and target DNAs PMID: 26887497
Subcellular Location
[Matrix protein p19]: Virion.; [Capsid protein p27, alternate cleaved 1]: Virion.; [Capsid protein p27, alternate cleaved 2]: Virion.; [Nucleocapsid protein p12]: Virion.
Database Links

KEGG: vg:2193432

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1